Next Generation HPLC: the Quest for Performance and Simplicity

Waters 2024 LC Symposium

Pushing the Boundaries of LC to Address Today’s Challenges

Overview

Today’s scientists and lab managers need to confidently deliver accurate, reliable, and reproducible data while facing increasingly complex molecules, aggressive sustainability goals, and accelerated timelines.

Join this free symposium to get insights from global LC thought leaders on the advancements of LC technology to address current challenges.

Day 2 – June 13 (10:00 AM EDT | 15:00 PM BST | 16:00 PM CEST)

Next Generation HPLC: the Quest for Performance and Simplicity

Advancements in HPLC technology impact routine testing laboratories where error reduction, ease of use and system performance play a crucial role. Our expert panel will discuss recent advances in HPLC technology, revisions to the USP <621> guidelines, application of Analytical Quality by Design (AQbD) software to assess method robustness, and innovative technologies which enhance simplicity and performance.

Learning objectives

• Hear from LC thought leaders about state-of-the-art LC technologies
• Learn how to control metal-based adsorption
• Explore orthogonal detection schemes
• Discover the next generation of intuitively simple LC systems

Join us for Waters 2024 LC Symposium, we are really looking forward to answering your questions in our live Q&A session and discussing this topic further with you.

Day 1 – June 12 (10:00 AM EDT | 15:00 PM BST | 16:00 PM CEST)

Advanced LC Technologies for Increasingly Complex Molecules

Our panel of industry leaders will discuss recent developments in liquid chromatography designed to meet today's analytical challenges. Our speakers will explore innovative technologies to mitigate unpredictable chromatography due to non-specific adsorption and explore the insights from light scattering detection.

Presenter: Davy Guillarme, Ph.D. (Sr Lecturer and Research Associate, University of Geneva)

Davy Guillarme, holds a Ph.D. in analytical chemistry from the University of Lyon, France, currently serves as a senior lecturer and research associate at the University of Geneva in Switzerland. With over 340 published journal articles in pharmaceutical analysis and h-index of 75, his expertise spans various techniques, including HPLC, UHPLC, HILIC, LC−MS, SFC, SFC-MS, multidimensional LC, and the analysis of biopharmaceuticals (proteins, mAbs, oligonucleotides, gene therapy products, mRNA…).

He is an associate editor of the Journal of Chromatography A and has been honored with the LC-GC Emerging Leader Award in Chromatography (2013), the Jubilee Medal from the Chromatographic Society (2018), and the International Award of the Belgian Society of Pharmaceutical Sciences (2022). His global recognition extends to being listed among the world's most influential analytical scientists by "Analytical Scientist" magazine in multiple years.

Presenter: Guilherme (Gui) Guimaraes, Ph.D. (Scientist, Biogen)

Dr. Guilherme (Gui) Guimaraes is a scientist in drug metabolism and pharmacokinetics at Biogen. He is responsible for bioanalytical analysis of small molecules and antisense oligonucleotides. Gui holds a Ph.D in pharmaceutical and biomedical sciences and a masters in international biomedical regulatory sciences from the University of Georgia. His graduate work was focused on the application of novel analytical strategies to improve the chromatographic performance and sensitivity of oligonucleotide LC-MS methods. Some of these strategies include the use of low adsorption surfaces and microflow LC-MS.

Presenter: Michelle Chen, Ph.D. (Sr Director, Research and Development, Waters l Wyatt Technology)

Dr. Michelle Chen is a senior director at Waters | Wyatt Technology located in Santa Barbara, California. Michelle obtained her Ph.D. from the Chemical Engineering Department at Yale University, where she focused on developing novel HPLC approaches for high-speed and high-efficiency separations of biopolymers. Since joining Wyatt, Michelle has incorporated multi-angle light scattering and dynamic light scattering detection with HPLC and field-flow fractionation, for characterizing synthetic and biological polymers, proteins, and nanoparticles. In recent years she has led the application team at Wyatt Technology to develop novel methods to characterize and quantify emerging therapeutics and delivery vehicles including new protein conjugates, viral vectors, lipid nanoparticles, and extracellular vesicles.

Presenter: Moderated by: Isabelle Vu Trieu (Pharmaceutical Market Development Manager, Americas, Waters Corporation)

Isabelle is a business development professional dedicated to delivering benefits to analytical scientists in the life sciences industry. With over 20 years of experience in providing chromatography and mass spectrometry solutions, Isabelle is particularly interested in helping pharmaceutical scientists achieve the data quality and integrity needed to drive decisions for drug quality, safety and efficacy. Isabelle joined Waters in 2009 and currently manages the development of the pharmaceutical market in the Americas. She holds Masters’ degrees in Chemistry from Columbia University and the University Claude Bernard in Lyon, France as well as a Chemical Engineering degree from Ecole Supérieure de Chimie Physique Electronique in Lyon, France.