RAFA 2021: Enhancing analysis of foods using the ACQUITY™ Premier solution, Vitamin B, Organic Acids and beyond

Waters recently launched ACQUITY™ Premier LC systems and columns that utilize the novel MaxPeak™ High Performance Surface (HPS) technology, which has been developed to mitigate metal analyte interactions in liquid chromatography. We have evaluated the performance of the ACQUITY™ Premier LC and columns for analysis of multiple B vitamins and organic acids and compared the results with those obtained using the conventional stainless-steel components.

We demonstrate significantly improved performance in analyte peak area, limit of quantification, and carry-over using the MaxPeak™ HPS technology in the analysis of not only the phosphorylated B vitamins, but also the non-phosphorylated B vitamins. Significant improvement in peak area was also observed in organic acid analysis.

Our results suggest that this novel technology brings a clear advantage over the conventional stainless-steel in the analysis of B vitamins and organic acids. This MaxPeak™ HPS technology has a high potential to improve the LC based analysis for a wide range of compounds in food testing.

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Presenter: Jinchuan Yang, PhD (Principal Scientist, Scientific Operations, Waters Corporation)

Dr. Jinchuan Yang is a principal scientist in the Scientific Operations at Waters corporation. He joined Waters in 2002. His roles at Waters have been mainly on the application development and marketing development as well as R&D and technology training support. His main focus is in the food and the environmental analysis areas using LC and UPC2 coupled with MS. He volunteers in technical groups at AOAC International and USP and serves as member of expert panels in these organizations.