Native Mode Analysis of Biologics- Charge Variant Profiling Protein Therapeutics Using Ion Exchange Chromatography (IEX) Solutions

As part of the life-cycle management of biotherapeutics, detailed analytical characterization needs to be performed to assess potential post translational modifications such as protein deamidation, pyroglutamate formation, lysine truncations, and oxidation. These analytical assessments are extremely important and are used to monitor and ensure product quality, safety and efficacy.

With increasing challenges to address assessment of these key critical quality attributes, Agilent Workflow Solutions make sure that you achieve your scientific compliance and business goals in Biopharmaceutical/ Biologics analysis.

In this webinar the presenter will discuss strategies for:

• Overview and importance of charge variant analysis of biotherapeutics
• Detailed Workflow solutions for Charge Variant Analysis
• How to minimize long and tedious buffer preparation by the use of specific software and automation
• How to optimize methods and save time for Intact analysis of antibodies by making the methods high throughput by using shorter and faster columns

Presenter: Dr. Sathish Kumar Lakshmipathy (Principal Investigator at BBRC, Syngene International)

Presenter: Debdip Ghosh (Business Development Manager, Chemistries and Supplies Division, Agilent Technologies)