Conventional analysis requires performing various processes such as column washing, equilibration at initial mobile phase concentrations, and the next sample injection by the autosampler during the analysis.
Therefore, demands have increased for LCMS systems that shorten the time spent for processes other than data acquisition in order to improve analytical throughput.
Shimadzu: Nexera MX
In an analysis of four biomarker compounds for the four major molecular species in the Cytochrome P450 family, the Nexera MX completed the analysis in only 38 seconds whereas conventional HPLC required one minute, 22 seconds.
The MX-DST incorporates a special flow line structure and instrument control system, and performs overlap control of sample injection by using two analysis systems (streams) alternately. As a result, after one system completes data acquisition, the other system starts data acquisition immediately, making it possible to use nearly the whole time of LCMS operation for data acquisition.
Shimadzu: Nexera MX Dual Stream Technology (MX-DST)
With LabSolutions Insight, the MRM chromatograms to be reviewed can be displayed in a stack. In addition, peak identification can be collectively processed via manual operation for peaks displayed. This reduces the time required for data processing, enabling more efficient data review.
Shimadzu: Processing Large Amounts of Data by LabSolutions Insight
LabSolutions Connect make full use of the high-throughput performance of Nexera MX. It seamlessly supports the series of operations from MRM optimization to batch queue execution, improving process efficiency.